Common side effects. If you have any questions about this medicine ask your pharmacist. In the November 2006 issue of "Drug Safety," Dr. Sabine Jeck-Thole and Dr. Wolfgang Wagner reported that betahistine hydrochloride may cause several allergic and skin-related side effects 1. The study authors suggest that hypersensitivity reactions may be a direct result of betahistine's role in increasing histamine levels throughout the body. Betahistine administered at doses of 24 mg/day between 3 and 90 days in neurectomized Menière patients demonstrated significant benefits in improving vestibular compensation (Redon et al., 2011). Boyd Bergeson has been writing since 2000 and has contributed to published research with the National Institute of Health and The Indian Health Board. Possible side effects. 2. © Patient Platform Limited. If the rash continues or is severe, contact your doctor for advice. Do not take two doses together to make up for a forgotten dose. The package insert for Serc states that patients may experience nervous system side effects, including convulsions, daytime sleepiness, confusion and hallucinations 2. Where possible, take the tablets with something to eat. The increased amounts of histamine released from histaminergic nerve endings stimulates H 1 receptors, thus augmenting the direct agonistic effects of betahistine on these receptors. Asthma: This medication may make the symptoms of breathing problems worse. Before using Betahistine Dihydrochloride Tablet, inform your doctor about your current list of medications, over the counter products (e.g. Although there is little evidence to prove that diet and lifestyle can help, these may be worth trying. The attacks can vary in severity, and in how often they occur. If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Betahistine medicine then it may not be safe to drive a vehicle or operate heavy machinery. The Driver and Vehicle Licensing Agency (DVLA) will allow driving again when your symptoms are well controlled. Important information about all medicines, Manufacturer's PIL, Serc® 8 mg and 16 mg tablets, British National Formulary, 77th Edition (Mar 2019), Remember to take your doses of betahistine with food, Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. I was placed on betahistine 12 mg bid around April and had significant reduction in balance and nausea issues, but continue to struggle with tinnitus and fragmented sleep. 1. Betahistine is belongs to a group of medications used to treat vertigo associated with Ménière's disease. Betahistine additionally dampens down the nerve signals sent from the inner ear to the brain relieving the symptoms of Ménière's disease. Do not keep out-of-date or unwanted medicines. How does this medication work? Other side effects listed in the package insert include low blood pressure and heart rhythm irregularities 2. Copyright © 2020 Leaf Group Ltd., all rights reserved. from the best health experts in the business. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. Swallow the tablet with a drink of water. They are usually mild and will stop by themselves. Patient Platform Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. In addition, betahistine has a powerful antagonistic effects at H 3 receptors, and increases the levels of neurotransmitters released from the nerve endings. If it does, it can then be continued. If you have ever had an allergic reaction to a medicine. Tell your doctor as soon as possible if you do not feel well while you are taking betahistine or if you have any questions or concerns. Betahistine Hydrochloride Side Effects Hypersensitivity and Allergic Reactions. What form(s) does this medication come in? Betahistine is belongs to a group of medications used to treat vertigo associated with Ménière's disease. 4. Patients experiencing chronic digestive problems may lower their dose to the minimum effective range and by taking betahistine with meals. Betahistine hydrochloride is a medication indicated for the treatment of Meniere's syndrome, which often results in vertigo, nausea, vomiting, hearing loss and inner ear inflammation. Never give it to other people even if their condition appears to be the same as yours. If you forget to take a dose, do not worry, just remember to take the next dose when it is due. It is generally a very safe medicine. The table below contains some of the most common ones associated with betahistine. If so, itâs important that you tell your doctor or pharmacist before you start taking betahistine. Betahistine hydrochloride works by altering the levels of histamine-1 and histamine-3 in the body, which can help dilate blood vessels in the brain that mediate some of the symptoms of Meniere's syndrome. Like all medicines, betahistine can cause side effects, although not everyone gets them. Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. Side effects of betahistine Medicines and their possible side effects can affect people in different ways. If you experience any other symptoms which you think may be due to the tablets, speak with your doctor or pharmacist for further advice. Initially 16 mg 3 times a day, dose preferably taken with food; maintenance 24â48 mg daily. Precautions Before taking betahistine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. ), allergies, pre-existing diseases, and current health conditions (e.g. Like all medicines betahistine can cause side effectsâ¦ The information on this page is written and peer reviewed by qualified clinicians. The study authors suggest that hypersensitivity reactions may be a direct result of betahistine's role in increasing histamine levels throughout the body. If you are taking any other medicines. The study by Jeck-Thole and Wagner also reports that patients may experience headache and liver problems, including increased liver enzymes and bile flow disturbances. 7. Possible side effects. You may not experience any of them. Betahistine (Bulk) 100 % Powder Side Effects by Likelihood and Severity Full Drug Information Selected from data included with permission and copyrighted by First Databank, Inc. If you are a driver, you must stop driving when Ménière's disease is diagnosed. Additional digestive problems may require that patients consult their physician in order to possibly find a suitable alternative. Possible side effects. It typically causes attacks of dizziness with a spinning sensation (vertigo), hearing loss and noises in the ear (tinnitus). Feeling sick (nausea), indigestion: Remember to take your doses of betahistine with food: Headache: Drink plenty of water and ask your pharmacist to recommend a suitable painkiller. These symptoms are usually not serious and subside in between doses. It may lead to an increase in the symptoms associated with a stomach ulcer. This reduces the amount of fluid in the inner ear and prevents symptoms from developing. Though Betahistine is a fairly safe drug with not many dangerous side effects, there are certain restrictions that you may have to follow when you take it. Description: Betahistine is a histamine analogue.The exact mechanism is not yet fully determined; however, it is known to act as both partial histamine H 1-receptor agonist and histamine H 3-receptor antagonist in neuronal tissue, with negligible histamine H 2-receptor activity.It may also improve the microcirculation in the labyrinth, thus reducing endolymphatic pressure.