Rabies is a rare but very serious infection of the brain and nerves. endstream endobj 723 0 obj <> endobj 724 0 obj <. Veteran. Although you can ask for titers of other diseases in lieu of vaccination, you cannot do that for rabies. A prospective subject should not be included in the study until the condition has resolved or the febrile event has subsided, Identified as an Investigator or employee of the Investigator or study center with direct involvement in the proposed study, or identified as an immediate family member (i.e., parent, spouse, natural or adopted child) of the Investigator or employee with direct involvement in the proposed study. The family of PUREVAX vaccines induce an effective immune response without the use of adjuvants that can present potential risks to cats. 2 Rabies vaccine Rabies vaccine is given to people at high risk of rabies to protect them if they are exposed. PureVax FeLV vaccine is the only nonadjuvanted FeLV vaccine utilizing canarypox-vectored vaccine technology. The appropriate public health official of the state of destination should be notified within 72 hours of any unvaccinated dog or cat imported into his or her jurisdiction. Rabies vaccine should either be a killed (Imrab 3, Merial) or a canary-pox vectored subunit vaccine, and should be administered at 4–6 months of age and boostered at 1 year of age. INDICATIONS: PUREVAX ® Feline Rabies 3 YR is recommended for the vaccination of healthy cats 12 weeks of age and older for prevention of disease due to rabies virus. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. PUREVAX Rabies is a vaccine that works by “teaching” the … Number of participants with rabies virus neutralizing antibody (RVNA) titer ≥ 0.5 IU/mL at Day 42 (14 days after the last vaccination of primary vaccination series). Immunogenicity and Safety of the Purified Vero Rabies Vaccine - Serum Free in Comparison With the Rabies Human Diploid Cell Vaccine (Imovax® Rabies) Administered in a Simulated Rabies Post-exposure Regimen in Healthy Adults: Study Start Date : June 2013: Actual Primary Completion Date : May 2014: Actual Study Completion Date : September 2014 Thread Starter Thread Starter #7 xocats TCS Member Thread starter. Often there is tingling and severe pruritus at the site of the animal bite. Safety and efficacy data are available which demonstrate that this vaccine can be administered the same day but not mixed with Boehringer Ingelheim adjuvanted vaccine against rabies. DOSAGE: Reconstitute the lyophilized vaccine with accompanying liquid diluent and aseptically inject … The incubation period of rabies in humans is generally 20–60 days. Rabid animals don't behave like normal animals - sometimes they're overly friendly or abnormally aggressive. Informed consent form has been signed and dated - Able to attend all scheduled visits and comply with all trial procedures. Boehringer Ingelheim Animal Health UK Ltd. Tel: Technical Enquiries: 01344 746957. Optimised safety profile with adjuvant-free protection for all components; Powerful immune response without adjuvant, thanks to its innovative canarypox technology for FeLV and rabies; INDICATIONS: PUREVAX ® Feline 4/Rabies is recommended for the vaccination of healthy cats 8 weeks of age and older for prevention of disease due to feline rhinotracheitis, calici, panleukopenia, and rabies viruses and as an aid in the reduction of disease due to Chlamydia psittaci. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Rabies or Rabies Purevax – Merial purevax rabies vaccine is given specifically to feline patients as part of the core vaccines. Rabies can be prevented by vaccinating pets, staying away from wildlife, and seeking medical care after potential exposures and before symptoms start. Information provided by (Responsible Party): Sanofi ( Sanofi Pasteur, a Sanofi Company ), Participants will receive the Purified Vero Rabies Vaccine (VRVg), Participants will receive the Imovax® Rabies vaccine, Rabies virus neutralizing antibody titer will be determined by the rapid fluorescent focus inhibition test (RFFIT). Rabies Vaccine, Pcec (PF) Suspension For Reconstitution Side Effects by Likelihood and Severity COMMON side effects If experienced, these tend to have a Less Severe expression Solicited systemic reactions: fever (temperature), headache, malaise, and myalgia. 10/15/13, 12/31/13, 4/25/17, 3/14/19, 9/1/20 . Purevax Rabies suspension for injection. Talk with your doctor and family members or friends about deciding to join a study. In this article, we provide a basic review of the 2 diseases, highl … Vaccination of Ferrets for Rabies and Distemper Vet Clin North Am Exot Anim Pract. Purevax Rabies, suspension injectable. Get the latest research information from NIH: You have reached the maximum number of saved studies (100). INDICATIONS: PUREVAX ® Feline Rabies is recommended for the vaccination of healthy cats 12 weeks of age and older for prevention of disease due to rabies virus. protection Most veterinary vaccines are adjuvanted inactivated vaccines and have been s … Three-year duration of immunity in cats vaccinated with a canarypox-vectored recombinant rabies virus vaccine Vaccine. In California, skunks and bats comprise over 90 percent of animal rabies cases reported each year. Revaccinate 1 year after first vaccination, then every 3 years. Rabies virus is maintained in populations of wild animals and occasionally spills over into domestic animals and humans. PUREVAX Rabies is a vaccine that works by “teaching” the … Adults should be vaccinated ever 1–3 years for FPV, FHV, FCV, and Rabies. PureVax Feline Rabies is the only nonadjuvanted feline rabies vaccine available as a standalone or in combination with other antigens. PUREVAX vaccines are designed for cats and kittens and deliver a robust, effective immune response without the need for adjuvants. DOSAGE: Reconstitute the lyophilized vaccine with accompanying liquid diluent and aseptically inject 1 mL (1 dose) subcutaneously into healthy cats. Sign up now . COVID-19 is an emerging, rapidly evolving situation. Jul 1, 2010. 298 Merial, Inc. Horses 1 3 mos Annually IM MYSTIQUE II Bayer Corp. License No. Rabies or Rabies Purevax – Merial purevax rabies vaccine is given specifically to feline patients as part of the core vaccines. Rabies vaccine should either be a killed (Imrab 3, Merial) or a canary-pox vectored subunit vaccine, and should be administered at 4–6 months of age and boostered at 1 year of age. PureVAX Feline Rabies 1 Rabies Vaccine, Live Canarypox Vector, cats 8 weeks and older No information is available on the safety and efficacy of this vaccine when used with any other veterinary medicinal product except the products mentioned above. Study record managers: refer to the Data Element Definitions if submitting registration or results information. with co-administration of human rabies immunoglobulins (Imovax® Rabies). In domestic animals, the incubation period is generally 3--12 weeks but can range from several days to months, rarely exceeding 6 months (7). one at Day 0, at Day 3, at Day 7, at Day 14 and at Day 28, respectively, (Essen regimen). PUREVAX FELINE 4/ RABIES Produced by: Merial Inc. License No. Still, it is vital to vaccinate your ferret against rabies. The new formulation, used in their line of PUREVAX® vaccines, purports to provide protection from the rabies virus for three years without the help of adjuvants that were used in … Regardless of the age at first vaccination, a booster should be administered 1 year later. Purevax Rabies suspension for injection. Rabies titer testing is used for pets who are being exported to rabies-free portions of the world to determine that the pet has been recently vaccinated against rabies, not as evidence of protective immunity. PUREVAX vaccines are the only complete line of nonadjuvanted feline vaccines available. Like other inactivated vaccines, the initial dose of a rabies vaccine serves as the “priming” dose. The .gov means it’s official. Given at sixteen weeks of age for kittens or any age for adults with unknown vaccine status. Most importantly, rabies is a fatal disease for people or any animal unlucky enough to be exposed through a bite or scratch to the saliva of a rabid animal, so extra precautions must be taken to protect us all. Merial is the global leader in rabies prevention with a range of vaccines for pets, farm animals and wildlife, including the IMRAB ® Rabies vaccines and the PUREVAX ® Feline Rabies vaccines. Protection starts at the latest four weeks after the injection and lasts for a year. Serum antibody titers can be monitored to evaluate response to the vaccination. By Company. DOSAGE: Reconstitute the lyophilized vaccine with accompanying liquid diluent and aseptically inject 1 mL (1 dose) subcutaneously into healthy cats. Booster products should not be used more frequently than the labeled duration of immunity. Although not common in ferrets, both viruses are fatal in ferrets and rabies virus is also fatal in humans. PUREVAX FELINE 4/ RABIES Produced by: Merial Inc. License No. Datasheet & Company Info. Rev. The conditional admission of such animals into the United States is subject to state and … Drug information provided by: IBM Micromedex. PUREVAX Rabies vaccine was developed using state-of-the-art technology just for cats and kittens. Rabies virus vaccine is an exception. Merial has identified an issue in recently manufactured lots of PUREVAX Feline Rabies vaccine and combinations, in which there may be irregularities in the physical appearance of the … An adjuvant is a substance that is added to a vaccine to increase the body's immune response to the vaccine. Rabies in ferrets has a relatively low number of documented cases in the United States(less than 20 since the 1950s), and infection worldwide is fairly rare. Although not common in ferrets, both viruses are fatal in ferrets and rabies virus is also fatal in humans. Adults should be vaccinated ever 1–3 years for FPV, FHV, FCV, and Rabies. Anti-rabies vaccination of pet carnivores • Sanitary requirement for intra-EU movements • Sanitary requirement for live introduction of pet carnivores in the EU Regulation (EC) 998/2003 of 26 May 2003 on the animal health requirements applicable to the non-commercial movements of pet animals and amending Council Directive 92/65/EEC . Purevax Rabies vaccine (Mérial) EPAR summary : • Rabies recombinant canarypos virus (vCP65) • Date of issue of Market autorisation (EMA) : 18/02/2011 • Used to vaccinate cats • Protection starts at the latest four weeks after the injection […] Problem : EU requirements injection Purevax Rabies 21 days 28 days valid? Purevax Rabies Vaccination - $32.00* Microchip for Dogs and Cats (Free Lifetime Registration) - $30.00* Biohazard Disposal Fee (EACH PATIENT) - $4.00; Office Visit Wellness Exam – $25; Office Visit Extended Time- $45* (Each Sick Patient ) Vanguard crLyme Disease Vaccine-$46* Heart worm Test, 4DX Test, FELV/FIV Test, Radiographs, Lab services ; Fleas, Ticks, & Heart worm Prevention; In … [ Time Frame: Day 14 post-vaccination ], Number of Participants Reporting Solicited Injection Site Reactions, Solicited Systemic Reactions, Unsolicited Systemic Reactions, and Serious Adverse Events Occurring Throughout the Trial [ Time Frame: Day 0 up to 6 months post-vaccination ], Geometric mean titer ratio (GMTR) following vaccination with either Purified Vero Rabies Vaccine, Serum Free or Rabies Human Diploid Cell Vaccine in a Simulated Rabies Post exposure Regimen [ Time Frame: Day 14 post-vaccination ], Aged 18 to < 65 years on the day of inclusion. Side Effects. Prevention of rabies in dogs and cats is key for reducing the risk of transmission of this deadly disease to humans. Serum antibody titers can be monitored to evaluate response to the vaccination. In California, skunks and bats comprise over 90 percent of animal rabies cases reported each year. Given at sixteen weeks of age for kittens or any age for adults with unknown vaccine status. 298 : Marketed by: Merial Inc. Cats N/A 1 ml SC 8 weeks 3-4 weeks later, then annually Adapted from the Compendium of Animal Rabies Prevention and Control, 2011, National Association of State Public Health Veterinarians, Incorporated . Free E-newsletter Subscribe to Housecall. Joined Mar 26, 2005 Messages 20,608 Reaction score 16. Pack Type Box. Sections. PUREVAX vaccines deliver a robust, effective immune response without the need for adjuvants. Chaque dose de 1 mLcontient: Substance active : Virus canarypox recombinant de la rage (vCP65) ≥ 10 6.8 FAID* 50 *Dose infectieuse 50 % par immunofluorescence . Purevax Feline 3 Year Rabies, VSCF Only. Compendium of Animal Rabies Prevention and Control, 2016; Rabies Compendium: Introductory Letter; Prospective Serologic Monitoring Protocol; For more information about the Rabies Compendium, please contact [email protected] With the exception of the canarypox-virus vectored vaccine against feline rabies (PUREVAX ® Feline Rabies and PUREVAX ® Rabies, Merial), all rabies vaccines currently marketed for companion animals are inactivated adjuvanted vaccines. The incubation period is highly variable. The donated doses supported a mass dog vaccination campaign in Madagascar. Pack Type Box. First and foremost, a rabies vaccine will prevent against infection, which though slim, can still happen. In 2018, Boehringer Ingelheim donated 75,000 doses of rabies vaccine to the Global Alliance for Rabies Control (GARC) in recognition of World Rabies Day on September 28. Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT01877395. To describe the geometric mean titer ratio (GMTR) between the 2 vaccine groups at Day 14. Federal government websites often end in .gov or .mil. Merial has identified an issue in recently manufactured lots of PUREVAX Feline Rabies vaccine and combinations, in which there may be irregularities in the physical appearance of the … Confirmed rabies has occurred as long as 7 years after exposure, but the reasons for this long latency are unknown.The first signs of illness are nonspecific: fever, anxiety, and malaise. To demonstrate that VRVg is non-inferior to Imovax® Rabies in terms of proportion of subjects achieving a rabies virus neutralizing antibody (RVNA) titer ≥ 0.5 international units (IU)/mL at Day 14. PUREVAX feline vaccines help protect cats against a number of diseases, including rabies, feline leukemia virus (FeLV), panleukopenia, and pathogens that commonly cause respiratory disease in cats. Kittens should be first vaccinated at 12 weeks/3 months of age. The aim of the study is to document the safety and immunogenicity of Purified Vero Rabies Vaccine (VRVg) when given in a simulated post-exposure regimen, i.e. Purevax Rabies suspension for injection. Rabies Vaccine (Intramuscular Route) Print. Supplied By: Merial (73088) SKU 066072. To assess the clinical safety of each vaccine after each vaccine injection when administered in a simulated post-exposure schedule. To demonstrate that the observed proportion of subjects achieving an RVNA titer ≥ 0.5 IU/mL at Day 14 is at least 99%, with a lower limit of the 95% confidence interval (CI) of at least 97%. Vaccination against rabies is considered core wherever rabies infection is endemic in any species or vaccination is mandated by law. Like other inactivated vaccines, the initial dose of a rabies vaccine serves as the “priming” dose. Safety will be assessed in all participants up to 28 days after vaccination, as applicable, in terms of occurrence of adverse events (AEs), and serious adverse events (SAEs) and adverse events of special interest (AESIs) up to 6 months post-vaccination 5. PUREVAX vaccines are the only complete line of nonadjuvanted feline vaccines available. Datasheet & Company Info. 298 : Marketed by: Merial Inc. Cats N/A 1 ml SC 8 weeks 3-4 weeks later, then annually Adapted from the Compendium of Animal Rabies Prevention and Control, 2011, National Association of State Public Health Veterinarians, Incorporated . In addition, human rabies immunoglobulins (HRIG) will be concomitantly administered to all subjects on Day 0. Sections. To help protect cats from Feline Panleukopenia, Feline Upper Respiratory Disease Complex, Rabies, and Feline Leukemia. PureVax Feline Rabies is the only nonadjuvanted feline rabies vaccine available as a standalone or in combination with other antigens. : 1 ml Indications Chez les chats âgés d'au moins 12 semaines : immunisation active contre la rage afin de prévenir la mortalité. Composition Suspension injectable : Virus Canarypox recombinant de la rage (vCP65) : ≥10 6,8 FAID 50 Excipients q.s.p. 10/15/13, 12/31/13, 4/25/17, 3/14/19, 9/1/20 . Boostered annually. Case Qty 1. Rabies virus is maintained in populations of wild animals and occasionally spills over into domestic animals and humans. Listing a study does not mean it has been evaluated by the U.S. Federal Government. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. Unit of Measure 10 x 1 Dose. The new formulation, used in their line of PUREVAX® vaccines, purports to provide protection from the rabies virus for three years without the … With the exception of the canarypox-virus vectored vaccine against feline rabies (PUREVAX ® Feline Rabies and PUREVAX ® Rabies, Merial), all rabies vaccines currently marketed for companion animals are inactivated adjuvanted vaccines. PureVax rabies contains no adjuvant, which (adjuvant) is thought to possibly be the cause of VAS (vaccine associated sarcoma) Adjuvant is what makes the vaccine stay longer in the body. Rabies is found throughout the world, particularly in Asia, Africa, and Central and South America. Purevax Rabies is used to vaccinate cats from 12 weeks of age to protect against rabies infection. The vaccine delivers everything needed to induce immunity without any of the unnecessary adjuvants that have posed risk to feline patients in the past, such as injection site reactions, chronic inflammation, and sarcoma formation. The Rabies Challenge Fund further contends that all states should have medical exemption clauses in their rabies laws/regulations allowing veterinarians to write waivers of rabies vaccinations for animals they have determined within the framework of a current client-patient relationship to be too ill or had a documented prior serious adverse reaction to the rabies vaccine. Vaccin contre la rage pour chats. PureVAX Feline Rabies 1 Rabies Vaccine, Live Canarypox Vector, cats 8 weeks and older Contact Us. PUREVAX ® is the only fully adjuvant-free feline vaccine range and provides:. PUREVAX ®. PUREVAX vaccines deliver a robust, effective immune response without the need for adjuvants. Solicited injection site reactions: pain, erythema, and swelling. Rev. Supplied By: Merial (73088) SKU 066072. PUREVAX® Rabies Outage Page 1 Dear Doctor: I am writing to share some important information regarding Merial PUREVAX® Feline Rabies vaccines. Source : RCP du 04/12/2015. with co-administration of human rabies immunoglobulins (Imovax® Rabies). Please feel free to share this information with your members. COMPOSITION QUALITATIVE ET QUANTITATIVE. Rabies virus usually is transmitted from animal to animal through bites. Unit of Measure 10 x 1 Dose. Please feel free to share this information with your members. KP3+FeLV: (under 12 weeks) Includes 3 exams; initial & 2 FVRCP (Feline Rhinotracheitis / Calici / Panleukopenia) booster vaccinations; initial & booster FeLV (Feline Leukemia); PureVax Rabies vaccine; deworming. Case Qty 1. Rabies is communicable during the period of salivary shedding of rabies virus. In this article, we provide a basic review of the 2 diseases, highl … Vaccination of Ferrets for Rabies and Distemper Vet Clin North Am Exot Anim Pract. PUREVAX Rabies vaccine was developed using state-of-the-art technology just for cats and kittens. All dogs and cats imported from countries with endemic rabies should be currently vaccinated against rabies as recommended in this Compendium. The items in bold print are recommended for every cat. It's not found in the UK, except in a small number of wild bats. Why Should I Register and Submit Results? 2933 Gunn Rd. Read our, ClinicalTrials.gov Identifier: NCT01877395, Interventional The incubation period is highly variable. Rabies virus vaccine is an exception. Prince … Rabies (Purevax) – booster every 3 years; Feline leukemia – booster every year; Deworming medication (if fecal examination positive) Heartworm medication; Flea and tick prevention (if outdoors) Senior screening tests * or at the 1 year anniversary of the last vaccine received as a kitten. Inactivated vaccines are very efficient at protecting dogs and cats against rabies. Prevention and control of rabies in bats and terrestrial mammals pose considerable challenges. 52 Bayer Corp. Horses 1 3 mos Annually IM C) ORAL (Rabies Glycoprotein, Live Vaccinia Vector) — RESTRICTED TO USE IN STATE AND FEDERAL RABIES … Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. Interested to learn more? Please remove one or more studies before adding more. 2. Side Effects. Keywords provided by Sanofi ( Sanofi Pasteur, a Sanofi Company ): Biological: Purified Vero Rabies Vaccine (VRVg), Biological: Imovax® Rabies: inactivated rabies vaccine. The vaccine delivers everything needed to induce immunity without any of the unnecessary adjuvants that have posed risk to feline patients in the past, such as injection site reactions, chronic inflammation, and sarcoma formation. Description and Brand Names; Before Using; Proper Use; Precautions; Side Effects; Products and services. The PUREVAX Feline Rabies vaccines and PUREVAX Recombinant FeLV vaccine (feline leukemia virus) vaccine have been developed using state-of-the-art technology to provide safe and effective vaccines for these diseases without the use of adjuvants. Choosing to participate in a study is an important personal decision. Purevax Rabies suspension for injection; Qualitative and quantitative composition; Pharmaceutical form ; Clinical particulars; Pharmaceutical particulars; Marketing Authorisation Holder … By Company. If a dog, after having received only 1 dose of rabies vaccine, is subsequently exposed to virulent rabies virus, exposure to the virulent virus then serves as the second, or immunizing, “dose.” Revaccinate annually with a single 1 mL dose. XÁ3/9¿¨ ¿(±$5¨jð»%V*¸'ææ&*é‘èr" (,!¬Ï!à0b;C€äÒ¢2(“‘ɘ À IÆ8/ A 1-ml dose of Purevax Rabies is injected under the skin. Rabies titer testing is used for pets who are being exported to rabies-free portions of the world to determine that the pet has been recently vaccinated against rabies, not as evidence of protective immunity. To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor. Includes 3 exams; initial & 2 FVRCP (Feline Rhinotracheitis / Calici / Panleukopenia) booster vaccinations; PureVax Rabies vaccine & deworming. 298 Merial, Inc. Cats 1 8 wks & 1 yr later Annually SC EQUINE POTOMAVAC+ IMRAB Merial, Inc. License No. For general information, Learn About Clinical Studies. Free E-newsletter Subscribe to Housecall. Inactivated vaccines are very efficient at protecting dogs and cats against rabies. Boostered annually. The first injection should be given in cats aged at least 12 weeks. More Info; Compare; ON PROMOTION; Login {{promo.PromoName}} {{promo.PromoText}} {{promo.StartDate | date : 'MM/dd/yyyy'}} - {{promo.EndDate | date : 'MM/dd/yyyy'}} Nov- 2020 Oct- 2020 Sep- 2020 Aug- 2020 Jul- 2020 Jun- 2020 May- 2020 Apr- … Merial, Ltd. has released a new rabies vaccine for cats, apparently in response to veterinarian and owner concerns about the safety of added adjuvants, substances that are intended to increase the immune response mounted by a cat after receiving a vaccine. Purevax Rabies Vaccination - $32.00* Microchip for Dogs and Cats (Free Lifetime Registration) - $30.00* Biohazard Disposal Fee (EACH PATIENT) - $4.00; Office Visit Wellness Exam – $25; Office Visit Extended Time- $45* (Each Sick Patient ) Vanguard crLyme Disease Vaccine-$46* Heart worm Test, 4DX Test, FELV/FIV Test, Radiographs, Lab services ; Fleas, Ticks, & Heart worm Prevention; In …  (Clinical Trial), Immunogenicity and Safety of the Purified Vero Rabies Vaccine - Serum Free in Comparison With the Rabies Human Diploid Cell Vaccine (Imovax® Rabies) Administered in a Simulated Rabies Post-exposure Regimen in Healthy Adults, Experimental: Purified Vero Rabies Vaccine Group, Experimental: Imovax® Rabies Vaccine Group, Pembroke Pines, Florida, United States, 33026, South Miami, Florida, United States, 33143, Raleigh, North Carolina, United States, 27612. Genetic and Rare Diseases Information Center, U.S. Department of Health and Human Services, The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. PureVax FeLV vaccine is the only nonadjuvanted FeLV vaccine utilizing canarypox-vectored vaccine technology. Rabies Vaccine (Intramuscular Route) Print. The cats should be revaccinated every year. PUREVAX, for the protection of felines. Subject is pregnant, or lactating, or of childbearing potential (to be considered of non-childbearing potential, a female must be post-menopausal for at least 1 year, surgically sterile, or using an effective method of contraception or abstinence from at least 4 weeks prior to the first vaccination and until at least 4 weeks after the last vaccination), Participation at the time of study enrollment or planned participation during the present trial period in another clinical trial investigating a vaccine, drug, medical device, or medical procedure, Receipt of any vaccine in the 4 weeks preceding the first trial vaccination or planned receipt of any vaccine during the course of the trial, Previous vaccination against rabies (in pre- or post-exposure regimen) with either the trial vaccine or another vaccine, Receipt of immunoglobulins, blood or blood-derived products in the past 3 months, Known or suspected congenital or acquired immunodeficiency; or receipt of immunosuppressive therapy, such as anti-cancer chemotherapy or radiation therapy, within the preceding 6 months; or long-term systemic corticosteroid therapy (prednisone or equivalent for more than 2 consecutive weeks within the past 3 months), Self-reported seropositivity for Human Immunodeficiency Virus (HIV), Hepatitis B, or Hepatitis C, At high risk of rabies infection during the trial, Known systemic hypersensitivity to any of the components of either vaccine or HRIG, or history of a life-threatening reaction to the vaccines used in the trial or to a vaccine containing any of the same substances, Self-reported thrombocytopenia, contraindicating intramuscular (IM) vaccination, Bleeding disorder, or receipt of anticoagulants in the 3 weeks preceding inclusion, contraindicating IM vaccination, Deprived of freedom by an administrative or court order, or in an emergency setting, or hospitalized involuntarily, Chronic illness that, in the opinion of the Investigator, is at a stage where it might interfere with trial conduct or completion, Moderate or severe acute illness/infection (according to investigator judgment) on the day of vaccination or febrile illness (temperature ≥ 100.4°F).